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BIOLOGY WITH HAMZA · MDCAT REVISION

Digestion

Name: ____________________   Date: ______________

Recall first. Check second. Return to the ideas you missed.

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Learning targets

Core notes

Read, cover and redraw

The digestive route
01Mouth

Chewing and the start of starch digestion.

02Stomach

Acid, mixing and protein digestion.

03Small intestine

Most chemical digestion and absorption.

04Large intestine

Water and ion recovery; faeces formation.

Different regions specialise through structure, secretions, enzymes and transit time.

Written recall

1. Why does emulsification increase lipid-digestion rate without breaking triglyceride bonds?

2. Why do most lipid products enter lacteals rather than blood capillaries directly?

Apply the idea

1. A fat-digestion experiment uses identical lipase amounts. Adding bile salts increases digestion rate. Which explanation is best?

  1. Emulsification increases the lipid–water interface accessible to lipase
  2. Bile salts are protein-digesting enzymes
  3. Bile salts supply extra lipase molecules
  4. Bile converts all fat directly into glucose

My answer: _____   Reason: ____________________________________

2. Most long-chain dietary lipids packaged into chylomicrons first enter which structure after leaving intestinal epithelial cells?

  1. Hepatic portal capillaries directly
  2. Lacteals
  3. The stomach lumen
  4. Renal tubules

My answer: _____   Reason: ____________________________________

3. Which enzyme is most consistent with these results under otherwise controlled conditions?

Protein breakdown by an unknown digestive enzyme
pHRelative activity
2100
75
91
  1. Pancreatic lipase
  2. Salivary amylase
  3. Pepsin
  4. Maltase

My answer: _____   Reason: ____________________________________

Answer key

Cover this section while attempting the questions.

Written recall

1. It divides fat into smaller droplets, increasing the surface area available for lipase action.

2. They are reassembled and packaged into particles that are too large for ordinary capillary entry and therefore move through lymphatic lacteals.

Applied questions

1. A — Bile salts help disperse large fat globules into smaller droplets. More accessible surface assists lipase; emulsification itself does not hydrolyse the triglycerides.

2. B — Chylomicrons enter intestinal lymphatic lacteals before reaching the bloodstream. Many water-soluble nutrients instead enter blood capillaries and the hepatic portal circulation.

3. C — High proteolytic activity in strongly acidic conditions fits pepsin, a stomach protease. The other listed enzymes digest different substrate classes.