MODEL
From filtrate to urine
Investigate water reabsorption and urine output.
Model
At 125 mL/min, change reabsorption from 99% to 98%. Why does final volume double?
Filtered water (L/day)180
Returned to blood (L/day)178.2
Final fluid (L/day)1.8
Final flow = filtered flow × fraction not reabsorbed. Convert mL/min to L/day by multiplying by 1.44. ADH can alter collecting-duct permeability; it does not filter blood directly.
Water-balance arithmetic only. No solute transport, secretion, changing hormones or clinical assessment is simulated.
Explain what you observed
How can you isolate the effect of one factor?
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Read a related learning guide →Practise Homeostasis →Open the student notes folder ↗Concepts and sources
Chapter extension: selected concepts, not complete syllabus coverage.
Read the supporting source ↗PMDC curriculum ↗Questions and explanations are original teaching material; these are not official exam questions.