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BUILD A PROCESS

Trace a secreted protein

Follow the endomembrane route.

Build a process

Use the up and down buttons to build the sequence, then check your reasoning. Some biological events overlap; follow the simplified pathway described here.

  1. 1
    Secretory vesicle fusion
  2. 2
    Golgi modification and sorting
  3. 3
    Transport vesicle to Golgi
  4. 4
    Translation at rough ER
  5. 5
    Transcription in the nucleus
Read the complete pathway
  1. Transcription in the nucleus. RNA is produced and processed before export.
  2. Translation at rough ER. A signal sequence directs the secretory protein into the ER.
  3. Transport vesicle to Golgi. Membrane vesicles move the new protein.
  4. Golgi modification and sorting. The Golgi sorts proteins for their destinations.
  5. Secretory vesicle fusion. Exocytosis releases the contents outside the cell.

Explain what you observed

Does this route pass through mitochondria?

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Your study notes

Take the next step

Connect this activity with your lesson notes and chapter practice.

Read a related learning guide →Practise Cell Structure & Function →Open the student notes folder ↗

Concepts and sources

Curriculum connections: 4.3. Selected concepts.

Read the supporting source ↗PMDC curriculum ↗

Questions and explanations are original teaching material; these are not official exam questions.

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